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Biofiltration Consulting

The global leader in downstream purification knowledge and consulting services.

BIOPROCESS CONSULTING

SEMINARS

(A) Learn TFF, Become Self-Sufficient, Then lead the pack

The Rozembersky Group offers training to enable your technical and manufacturing staff to confidently manage all aspects of your TFF development and operations. All training is custom tailored to your requirements and procedures, whether you are a startup company looking to evaluate separation technologies or a world leader in biopharmaceutical manufacturing. Current seminars offered include these:

(B) Enter the World of Tangential Flow Filtration (TFF).

This seminar introduces engineers and scientists to the capabilities of TFF. In this seminar, students learn:This seminar introduces engineers and scientists to the capabilities of TFF. In this seminar, students learn: (1) What TFF is and what are its capabilities and limitations (2) How does TFF compare to other separation technologies (3) TFF procedures—who, how, what, when, where, (4) A review of TFF components including membrane cassettes, (5) hardware, and process control equipment, (6) How to structure laboratory studies using TFF, and (7) Fundamental operation of TFF systems


(C) Teaching Your Technical Staff to be Self-Sufficient

This seminar helps process engineers, manufacturing engineers, and scientists take their TFF experience to the next level and become self-sufficient at higher level TFF tasks: (1) Understand the factors that improve performance and consistency, (2) How to optimize a TFF process, (3) How to test cleaning procedures and storage agents, (4) How to maximize the recovery of membrane cassettes, (5) How to properly run trials to evaluate new membranes and product fluids, (6) How to ensure linear scale-up from the lab to your production equipment


(D) Become an Expert in TFF - High Level Theory and Application

This seminar is for engineers and scientist who will be taking a leadership role in the development and implementation of TFF systems. After completing this course, participates will have the expertise to: (1) Understand membrane materials, chemical binding and absorption, (2) How TFF theory relates to real-life processing, (3) Developing correct and comprehensive TFF procedures using a minimum amount of time, money, and product, (4) Design a TFF process based on procedures, (5) Specify the hardware components required to manufacture a TFF system, (6) Specify membrane filters for a given TFF process, (7) Develop trials plans including lab to production scaleup (8) Optimize the system once it is in place, (9) Managing the TFF environment and technicians

 

Seminar Topics

Applied Principles & Techniques

(1) Factors Effecting Performance, (2) Modes of Operation, (3) Concentration, (4) Diafiltration, (5) Fractionation, (6) Gel Layer Dynamics, (7) Membrane Properties, (8) Types of Configurations

Cleaning & Validation

(1) Types of Cleaning & Storage Agents, (2) Factors affecting Cleaning, (3) Importance of Cleaning, (4) Membrane Recovery, (5) How to prove effectiveness and consistency

Standard Operating Procedures (SOP)

(1) Preconditioning, (2) Sanitization, (3) Process Prep, (4) Postconditioning, (5) Cleaning, (6) Flushing. (7) NWP, (8) Storage, (9) Critical Factors for Success

Integrity Testing

(1) Air Diffusion Rate, (2) Low P vs Hi P Analysis, (3) Pressure Hold Testing, (4) Diffusion Rate Analysis, (5) Method Testing

Scale-up

(1) Factors Critical for Linear Scaleup, (2) Linear vs Non-Linear, (3) Method Testing

Process System Design

(1) Critical Factors, (2) Linear vs Non-Linear, (3) Scale-up, (4) Conformance to SOP, (5) Capacity Consideration, (6) Bioburden Concerns

 

Services that Save you Money

Reduce Error-Driven Loses and Increase Profitability Through Optimization

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Contact

Rozembersky Group Inc.

Phone / Text: 508-397-9887

John@RozemberskyGroup.com

90 Biccentennial Way, Boxborough, MA. 01719